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New findings could help explain why MS affects more women than men

23 May 2014 3 min read

Published in 2014. Some details may be out of date. See the latest news.

A promising early study from the Washington University School of Medicine suggests that a protein called S1PR2 could play a role in allowing immune cells to enter the central nervous system and cause the damage that occurs in MS.

Researchers have found that the S1PR2 gene appears to be more active in women than in men, and also in regions of the brain that tend to be affected by MS.

Dr Emma Gray, Research Communications Manager at the MS Society, said: “We don’t yet fully understand why MS affects more women than men, and it’s an area that’s intrigued scientists, and people with MS, for many years. A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors – and this study explores one such genetic factor in further detail, which is really interesting.”

A promising early study from the Washington University School of Medicine suggests that a protein called S1PR2 could play a role in allowing immune cells to enter the central nervous system and cause the damage that occurs in MS.

Researchers have found that the S1PR2 gene appears to be more active in women than in men, and also in regions of the brain that tend to be affected by MS.

Dr Emma Gray, Research Communications Manager at the MS Society, said: “We don’t yet fully understand why MS affects more women than men, and it’s an area that’s intrigued scientists, and people with MS, for many years. A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors – and this study explores one such genetic factor in further detail, which is really interesting.”

A promising early study from the Washington University School of Medicine suggests that a protein called S1PR2 could play a role in allowing immune cells to enter the central nervous system and cause the damage that occurs in MS.

Researchers have found that the S1PR2 gene appears to be more active in women than in men, and also in regions of the brain that tend to be affected by MS.

Dr Emma Gray, Research Communications Manager at the MS Society, said: “We don’t yet fully understand why MS affects more women than men, and it’s an area that’s intrigued scientists, and people with MS, for many years. A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors – and this study explores one such genetic factor in further detail, which is really interesting.”

A promising early study from the Washington University School of Medicine suggests that a protein called S1PR2 could play a role in allowing immune cells to enter the central nervous system and cause the damage that occurs in MS.

Researchers have found that the S1PR2 gene appears to be more active in women than in men, and also in regions of the brain that tend to be affected by MS.

Dr Emma Gray, Research Communications Manager at the MS Society, said: “We don’t yet fully understand why MS affects more women than men, and it’s an area that’s intrigued scientists, and people with MS, for many years. A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors – and this study explores one such genetic factor in further detail, which is really interesting.”

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